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Tuberculosis, spinal

MedGen UID:
11948
•Concept ID:
C0041330
•
Disease or Syndrome
Synonyms: Disease, Pott; Disease, Pott's; Pott Disease; Pott's Disease; Potts Disease; Spinal Tuberculoses; Spinal Tuberculosis; Tuberculoses, Spinal; Tuberculosis, Spinal
SNOMED CT: Tuberculosis of spine (Pott's) (35984006); Tuberculosis of vertebral column - Pott's (35984006); Tuberculosis of vertebral column (35984006); Pott's disease (35984006); Tuberculous spondylitis (35984006)
 
Monarch Initiative: MONDO:0043836

Definition

Tuberculosis of the vertebrae. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTuberculosis, spinal

Professional guidelines

PubMed

Diagnosis and Treatment of Skipped Multifocal Spinal Tuberculosis Lesions.
Na S, Lyu Z, Zhang S
Orthop Surg 2023 Jun;15(6):1454-1467. Epub 2023 Apr 25 doi: 10.1111/os.13744. PMID: 37186216Free PMC Article
Current Study of the Detection and Treatment Targets of Spinal Tuberculosis.
Wang B, Gao W, Hao D
Curr Drug Targets 2020;21(4):320-327. doi: 10.2174/1389450120666191002151637. PMID: 31577205
Spinal tuberculosis: review of current management.
Dunn RN, Ben Husien M
Bone Joint J 2018 Apr 1;100-B(4):425-431. doi: 10.1302/0301-620X.100B4.BJJ-2017-1040.R1. PMID: 29629596

Recent clinical studies

Etiology

Diagnosis and Treatment of Skipped Multifocal Spinal Tuberculosis Lesions.
Na S, Lyu Z, Zhang S
Orthop Surg 2023 Jun;15(6):1454-1467. Epub 2023 Apr 25 doi: 10.1111/os.13744. PMID: 37186216Free PMC Article
Mycobacterial Musculoskeletal Infections.
Hogan JI, Hurtado RM, Nelson SB
Infect Dis Clin North Am 2017 Jun;31(2):369-382. Epub 2017 Mar 11 doi: 10.1016/j.idc.2017.01.007. PMID: 28292541
Early diagnosis of spinal tuberculosis.
Chen CH, Chen YM, Lee CW, Chang YJ, Cheng CY, Hung JK
J Formos Med Assoc 2016 Oct;115(10):825-836. Epub 2016 Aug 10 doi: 10.1016/j.jfma.2016.07.001. PMID: 27522334
Drug therapy in spinal tuberculosis.
Rajasekaran S, Khandelwal G
Eur Spine J 2013 Jun;22 Suppl 4(Suppl 4):587-93. Epub 2012 May 12 doi: 10.1007/s00586-012-2337-5. PMID: 22581190Free PMC Article
Spinal infections.
Tay BK, Deckey J, Hu SS
J Am Acad Orthop Surg 2002 May-Jun;10(3):188-97. doi: 10.5435/00124635-200205000-00005. PMID: 12041940

Diagnosis

Spinal Tuberculosis.
Heyde CE, Lübbert C, Wendt S, Rodloff A, Völker A, von der Höh NH
Z Orthop Unfall 2022 Feb;160(1):74-83. Epub 2021 Jan 21 doi: 10.1055/a-1285-4994. PMID: 33477180
Spinal Tuberculosis: Still a Great Mimic.
Garg RK, Malhotra HS, Kumar N
Neurol India 2019 Nov-Dec;67(6):1402-1404. doi: 10.4103/0028-3886.273618. PMID: 31857523
Spinal tuberculosis: a comprehensive review for the modern spine surgeon.
Khanna K, Sabharwal S
Spine J 2019 Nov;19(11):1858-1870. Epub 2019 May 15 doi: 10.1016/j.spinee.2019.05.002. PMID: 31102727
Spinal tuberculosis: review of current management.
Dunn RN, Ben Husien M
Bone Joint J 2018 Apr 1;100-B(4):425-431. doi: 10.1302/0301-620X.100B4.BJJ-2017-1040.R1. PMID: 29629596
Spinal tuberculosis.
de Nijs RN
Lancet 2011 Dec 3;378(9807):e18. Epub 2011 Oct 6 doi: 10.1016/S0140-6736(11)61482-7. PMID: 21982257

Therapy

Pott's disease (tuberculous spondylitis).
Pintor IA, Pereira F, Cavadas S, Lopes P
Int J Mycobacteriol 2022 Jan-Mar;11(1):113-115. doi: 10.4103/ijmy.ijmy_2_22. PMID: 35295033
Spinal Tuberculosis.
Chipeio ML, Sayah A, Hunter CJ
Am J Trop Med Hyg 2021 Mar 15;104(5):1605-1606. doi: 10.4269/ajtmh.20-1529. PMID: 33720843Free PMC Article
Cervical spine tuberculosis.
Teka M, Ghozlen HB, Zaier AY, Hnia MB, Naouar N, Abid F
Pan Afr Med J 2020;37:7. Epub 2020 Sep 2 doi: 10.11604/pamj.2020.37.7.25226. PMID: 32983325Free PMC Article
Spinal tuberculosis: a comprehensive review for the modern spine surgeon.
Khanna K, Sabharwal S
Spine J 2019 Nov;19(11):1858-1870. Epub 2019 May 15 doi: 10.1016/j.spinee.2019.05.002. PMID: 31102727
Drug therapy in spinal tuberculosis.
Rajasekaran S, Khandelwal G
Eur Spine J 2013 Jun;22 Suppl 4(Suppl 4):587-93. Epub 2012 May 12 doi: 10.1007/s00586-012-2337-5. PMID: 22581190Free PMC Article

Prognosis

Pott's disease (tuberculous spondylitis).
Pintor IA, Pereira F, Cavadas S, Lopes P
Int J Mycobacteriol 2022 Jan-Mar;11(1):113-115. doi: 10.4103/ijmy.ijmy_2_22. PMID: 35295033
Spinal Tuberculosis.
Heyde CE, Lübbert C, Wendt S, Rodloff A, Völker A, von der Höh NH
Z Orthop Unfall 2022 Feb;160(1):74-83. Epub 2021 Jan 21 doi: 10.1055/a-1285-4994. PMID: 33477180
Spinal tuberculosis: review of current management.
Dunn RN, Ben Husien M
Bone Joint J 2018 Apr 1;100-B(4):425-431. doi: 10.1302/0301-620X.100B4.BJJ-2017-1040.R1. PMID: 29629596
Spine infections.
Go JL, Rothman S, Prosper A, Silbergleit R, Lerner A
Neuroimaging Clin N Am 2012 Nov;22(4):755-72. Epub 2012 Oct 2 doi: 10.1016/j.nic.2012.06.002. PMID: 23122265
Spinal tuberculosis: a review.
Garg RK, Somvanshi DS
J Spinal Cord Med 2011;34(5):440-54. doi: 10.1179/2045772311Y.0000000023. PMID: 22118251Free PMC Article

Clinical prediction guides

Evaluation of different diagnostic methods for spinal tuberculosis infection.
Li Z, Wang J, Xiu X, Shi Z, Zhang Q, Chen D
BMC Infect Dis 2023 Oct 18;23(1):695. doi: 10.1186/s12879-023-08655-5. PMID: 37853312Free PMC Article
Spinal Tuberculosis.
Heyde CE, Lübbert C, Wendt S, Rodloff A, Völker A, von der Höh NH
Z Orthop Unfall 2022 Feb;160(1):74-83. Epub 2021 Jan 21 doi: 10.1055/a-1285-4994. PMID: 33477180
Bone and joint tuberculosis.
Pigrau-Serrallach C, Rodríguez-Pardo D
Eur Spine J 2013 Jun;22 Suppl 4(Suppl 4):556-66. Epub 2012 Jun 19 doi: 10.1007/s00586-012-2331-y. PMID: 22711012Free PMC Article
Spinal infections.
Tali ET
Eur J Radiol 2004 May;50(2):120-33. doi: 10.1016/j.ejrad.2003.10.022. PMID: 15081128
Osteomyelitis.
Laughlin RT, Wright DG, Mader JT, Calhoun JH
Curr Opin Rheumatol 1995 Jul;7(4):315-21. doi: 10.1097/00002281-199507000-00009. PMID: 7547109

Recent systematic reviews

Healing Assessment of Spinal Tuberculosis: A Systematic Review.
Sekhar Sethy S, Mittal S, Goyal N, Sudhakar PV, Verma V, Jain A, Verma A, Vathulya M, Sarkar B, Kandwal P
World Neurosurg 2024 May;185:141-148. Epub 2024 Feb 15 doi: 10.1016/j.wneu.2024.02.057. PMID: 38367856
Clinical outcomes and surgical strategy for spine tuberculosis: a systematic review and meta-analysis.
Arifin J, Biakto KT, Johan MP, Anwar SFZ
Spine Deform 2024 Mar;12(2):271-291. Epub 2023 Nov 17 doi: 10.1007/s43390-023-00785-9. PMID: 37975989Free PMC Article
Structural Versus Nonstructural Bone Grafting Via the Posterior Approach in the Treatment of Thoracic and Lumbar Tuberculosis: A Systematic Review and Meta-Analysis.
Zhong Y, Huang Y, Chen Z, Liu Z, Liu W, Luo J, Ye Y
World Neurosurg 2023 Jun;174:42-51. Epub 2023 Mar 10 doi: 10.1016/j.wneu.2023.03.021. PMID: 36906088
Treatment for tuberculosis of the subaxial cervical spine: a systematic review.
Yuan B, Zhao Y, Zhou S, Wang Z, Chen X, Jia L
Arch Orthop Trauma Surg 2021 Nov;141(11):1863-1876. Epub 2020 Aug 9 doi: 10.1007/s00402-020-03572-7. PMID: 32776174
Management of spinal tuberculosis: a systematic review and meta-analysis.
Zhang X, Ji J, Liu B
J Int Med Res 2013 Oct;41(5):1395-407. Epub 2013 Sep 17 doi: 10.1177/0300060513498023. PMID: 24045167

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